Elanco Advantage II Flea Treatment for Large Cats Over 9 lbs, 6 Monthly Doses

Six Months of Premium Flea Protection for Your Large Cat

Elanco Advantage II Flea Treatment is precisely formulated for large cats weighing over 9 lbs, delivering six full months of fast-acting, waterproof flea protection in every pack. Developed by Elanco, a trusted name in animal health, this topical treatment kills fleas on contact — so your large cat gets immediate relief without ever having to be bitten. Whether your cat is a bold indoor explorer or a confident lap companion, Advantage II keeps them comfortable, itch-free, and protected all month long.

Eliminates Fleas at Every Life Stage, Stops Reinfestation at the Source

Advantage II doesn't just kill adult fleas — its dual-action formula targets fleas at all life stages, including eggs and larvae, breaking the flea life cycle before it can spread through your home. Fast-acting within 12 hours of application, each dose provides a full 30 days of continuous protection. The waterproof formula stays effective through your cat's grooming and daily activity, so protection never lapses. With 6 doses per pack, you're covered for six full months of worry-free flea control.

Trusted by American Cat Owners, Ships Fast Across the USA

Elanco Advantage II is a cat-safe formula designed specifically for feline physiology — never use dog flea products on cats. This large cat formula (over 9 lbs) is safe and effective when used as directed. Application is simple: part the fur at the base of your cat's skull and apply the tube directly to the skin once a month. Each pack arrives new and sealed, ready to use. Orders ship fast within the US so your large cat's flea protection starts right away.